PhD in membrane protein chemistry

DTU Bioengineering
torsdag 24 maj 18

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Frist 15. august 2018
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A 3-year PhD position is available in the laboratory of Professor Preben Morth at the Technical University of Denmark. The aim is to understand how the lipid environment influences the activity of membrane proteins, using active transporters as benchmark systems, and to investigate the dynamic fluctuations between lipid and protein in solution and using state of the art biophysical methods and enzyme kinetic methods.

Responsibilities and tasks
We search for highly motivated individuals to work in the field of membrane protein chemistry. The ideal candidate has previous experience in membrane protein expression and purification for structural analysis as well as experience with enzyme kinetics and the use of fluorescence spectroscopy. Applicants with knowledge on membrane protein characterization using biophysical methods will be prioritized. The candidate should be self-motivated, have excellent interpersonal, communication skills and a demonstrated ability to interact effectively with staff at all levels within a multi-disciplinary team.

Laboratory tasks include:

  • Cloning including primer design PCR reaction, subcloning in both bacterial and cell lines
  • Expression, Protein purification of both soluble and membrane proteins
  • Functional charachterization of both soluble and membrane proteins
  • Crystallisation, data collection
Qualifications
  • Formal requirement with regard to education is a masters degree in biochemistry /molecular biology as minimum. Experience from similar work can replace this formal requirement
  • Experience with protein chemistry, protein crystallography and biophysical methods is preferred
  • Work knowledge of Word and Excel
  • The group has a number of international collaborations and the position requires applicants to be highly organized and fluent in English
  • Open and friendly nature, not afraid to learn something new

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Professor Jens Preben Morth at j.p.morth@ncmm.uio.no or +4741295885.

You can read more about “the Department” at www.bioengineering.dtu.dk

Application
Please submit your online application no later than 15 August 2018 (local time). Apply online at www.career.dtu.dk.

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:
  • A one-page statement of motivation and research interests
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)
  • Names and contact details of 2-3 references (name, relation to candidate, e-mail and telephone number)

Candidates may apply prior to ob­tai­ning their master's degree but cannot begin before having received it.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

The Department of Biotechnology and Biomedicine (DTU Bioengineering) conducts research, educates future bio-engineers, provides scientific advice and innovate within the areas of microbiology, biochemistry, biotechnology and biomedicine. The research at DTU Bioengineering is at the highest international level and focuses on the societal and scientific challenges within the field. Research is conducted within three main areas: Microbial ecology and physiology, Industrial biotechnology and cell factories, and Biomedicine and health. The department has extensive collaboration with national and international research units and industries. DTU Bioengineering has approx. 160 employees, of which 2/3 is scientific staff, and is expanding rapidly in 2018. The department is located at DTU Lyngby Campus.

DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government and public agencies.