Postdoctoral Researcher in Protein Engineering and Glyco-mimetics

Thursday 26 Sep 19

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The Section of Protein Science and Biotherapeutics at the Department of Biotechnology and Biomedicine has an opening for a position as postdoctoral researcher. The position will be available from November 2019 or soon thereafter.

 

The successful applicant will work within the newly established research group ‘Glycoengineering and Innovation’ headed by Professor Steffen Goletz and is partially funded by a NNF Strategic Award.

 

In our research group, we apply and develop advanced glycoengineering technologies to elucidate the role of glycosylations for the microbiome, disease and complex immunological networks and use these for identifying novel drug targets and generating novel drug candidates and therapeutic strategies. Our focus lies within glycoimmunology, microbiome glycoengineering, glycomic and glycomimetic display systems as well as molecular and cellular glycoengineering, antibody engineering,phage display technologies, and mammalian bioprocess engineering.

 

Responsibilities and tasks

Within the NNF funded research program of Glycoengineering of the Microbiome the newly recruited postdoctoral researcher will have the potential to lead the line of research in:

Glycoprotein- and carbohydrate-mimetics using phage display with molecular evolution and proteinengineering

In this project, we will generate novel protein-based mimetics of carbohydrate structures and receptors. It includes generation of novel phage-display libraries and molecular evolution as well as complex antibody and fusion-protein engineering and conjugation for generation of new therapeutic strategies especially in the area of anti-infectives.

 

Qualifications

Applicant should hold a PhD in a life sciences discipline, have excellent communication skills and be extensively trained in antibody and fusion-protein engineering, phage display and molecular evolution, protein expression in and purification from mammalian and bacterial cell systems, as well as broad spectrum of immune-based assays and coupling techniques. Prior successful postdoctoral research and supervision of PhD students is not mandatory but would be highly advantageous, and knowledge in bioreactor processes, USP and DSP would be a strong asset. The ideal candidate would be also familiar with anti-infectives and/or auto-immune diseases.

 

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.


Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.


You can read more about career paths at DTU here.


The position will be located at the DTU Lyngby campus in the recently established research building 225 hosting state-of-the-art laboratories for e.g. protein science, phage display, microbiome research, immunology and cellular research, mammalian bioprocessing as well as the DTU Proteomics Core.

 

The position is for 3 years.

 

Further Information

Additional information may be obtained from Prof. Dr. Steffen Goletz, Vice Director of the Institute, sgoletz@dtu.dk

 
Please submit your online application no later than 10 November 2019 (local time).

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Diploma (MSc/PhD)
  • List of publications

Applications and enclosures received after the deadline will not be considered.


All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.


DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent university collaborating globally with business, industry, government and public agencies.