Laboratory Technician in Biochemistry and Protein Science

Thursday 29 Oct 20

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The Tropical Pharmacology Lab, based in the section for Protein Science & Biotherapeutics (PSBT), at the Department of Biotechnology and Biomedicine at the Technical University of Denmark is looking for a Laboratory Technician within the fields of biochemistry and protein science for a 5 years position.

Associate Professor Andreas Hougaard Laustsen heads the research group and you will work in a team of scientists and laboratory technicians in an extraordinarily ambitious antibody development project with the aim of developing a fully recombinant antivenom against snakebite for sub-Saharan Africa.

Responsibilities and tasks
The project is funded by Wellcome and has the aim of delivering tangible human health impact via the development of novel snakebite therapeutics. Your role will be to support a team of 1 senior scientist, 4 postdoctoral scientists, and 1 other laboratory technician working on toxin biochemistry, antibody and nanobody discovery, and biophysical characterization of antibodies with the purpose of developing a recombinant oligoclonal antibody cocktail that can neutralize the venoms of the medically most important snakes of sub-Saharan Africa. The project will thus be highly collaborative, and you will be involved in performing laboratory experimentation within biochemistry and protein science, such as SDS-PAGE, chromatography, characterization of protein-protein interactions, biophysical characterization of proteins, and related techniques.

As part of a technician team of eight across the Section for Protein Science and Biotherapeutics you will in addition to the research project responsibility, be involved in laboratory management, procurement, safety tasks, and instructing/supervising students and young researchers.

Our expectations
We welcome applicants with all levels of experience, but expect that you can demonstrate excellent laboratory skills within immunology and molecular microbiology.

It is expected that the you have experience with several of the following techniques:

  • SDS-PAGE
  • Western blot
  • Enzymatic assays
  • Chromatography (HPLC, FPLC, SEC, IEC, IMAC)
  • Proteomics (MS/MS) and mass spectrometry for proteins
  • Biophysical characterization of proteins and protein-protein interactions (SPR, ITC, SEC, DSC etc.)
  • Cloning
  • Recombinant protein expression and purification
  • ELISA
  • PCR

In our research group, we highly value collaboration, and it will be expected that you can demonstrate an ability to collaborate with your peers/colleagues. Training and experience from industry is also appreciated.

We expect you are a trained laboratory technician, flexible with a positive approach to a dynamic and ever changing research environment. You have the knowledge and experience with work and safety in a laboratory environment with many international employees.

Candidates with a degree at MSc level or above will not be considered.

Assessment
In the assessment of the candidates, consideration will be given to:

  • Experience with biochemistry
  • Experience with protein science and molecular biology
  • Collaboration skills
  • Communication skills

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

More specifically in the Tropical Pharmacology Lab, we are a group of high performing scientists that share the vision that science is supposed to benefit humankind, especially underprivileged societies and/or societal groups. This shared vision with a very international outreach has created an academic environment that is ambitious and innovative fueled by an exceptionally collegially supportive attitude to both people and their work. We welcome people with all types of backgrounds and strive for diversity. Our research group is highly active in numerous outreach activities and our international travel agendas are typically busy. Finally, group members typically have an entrepreneurial attitude, resulting in the establishment of a number of spin-out biotech companies by group members.

See more: www.tropicalpharmacology.com

Salary and terms of employment
Salary and employment conditions based on the OAO-S joint agreement and association agreement for office workers, laboratory technicians and IT staff (HK/Stat) signed with the Danish Ministry of Finance.

The position is full time, but a part-time employment can be negotiated: Start date 1st of February 2021 (or soon thereafter) with an end date 31st of January 2026.

The positions will be located at the DTU Lyngby campus in a newly established research building hosting ultra-modern laboratories for antibody discovery and phage display technology with neighboring laboratories with state-of-the-art facilities for protein science and proteomics.

Further Information
Additional information may be obtained from Assoc. Prof. Andreas Hougard Laustsen, ahola@bio.dtu.dk or Lab Manager Lene Holberg Blicher mail: lench@dtu.dk phone: +45 45258610.

You can read more about the department at www.bioengineering.dtu.dk

Application procedure
Please submit your online application no later than 30 November 2020 (Danish time).

To apply, please open the link "Apply online," fill out the application form; attach a cover letter outlining your motivation for the application, CV with references and diplomas. The application may be written in Danish or English.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Bioengineering
The Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in the areas of biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science industry and point towards innovation, new businesses and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 210 employees, of which 2/3 are scientific staff. The department is located at DTU Lyngby Campus.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,000 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. Our main campus is in Kgs. Lyngby north of Copenhagen and we have campuses in Roskilde and Ballerup and in Sisimiut in Greenland.