The LAMINATE group has expertise in areas of epidemiology and pathogenesis of food borne pathogens; on host-bacterial pathogens interaction and on process development from a tube to a microchip and applied micro-nanotechnology for rapid detection of pathogens (virus and bacteria).
The group has worked on several projects on development of different approaches for sample preparation and concentration using antibodies, aptamers and protein based capturing agents immobilized on polymer based 3D sponge structure, magnetic beads, and nano particles.
The group has expertise in developing strategies for immobilization of biomolecules with controlled orientation to enhance the functional efficiency such as immuno-affinity reactions in food, fecal, environmental and blood matrix.
The group has involved in different EU and National project to develop process development and integration for Lab-on-a-chip systems for nucelic acid based (DNA/RNA) analysis.
The research work has included DNA array for detection of Campylobacter, AIV and colon cancer; process development of total integrated PCR chip and system for detection of foodborne pathogens (Campylobacter, Salmonella, Listeria, Avian Influenza virus, Norovirus) in food, animal production and in human samples; Development of a highly-sensitive DNA hybridization platform using supercritical angle fluorescence measurement; On-chip dried reagents as ready to use for online or at site rapid detection and identification of pathogens; selection of appropriate dyes for real-time PCR, Real time Isothermal amplifications such as Loop mediated isothermal amplification (LAMP), development of novel DNA probe immobilisation strategies for multiplex detection by solid-phase PCR technique etc.