Postdoc in Advanced Nanobody Discovery Technologies

Monday 20 Dec 21

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Apply no later than 30 January 2022
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We are looking for a 3-year postdoctoral researcher within the field of nanobody discovery technologies from 1 March 2022 (or soon thereafter). The positions will involve laboratory work, collaboration with both academic and industrial partners in the ColiShield consortium: Bactolife ApS, Lone Gram (DTU), and Jakob Møller-Jensen (University of Southern Denmark.

The Tropical Pharmacology Lab
The Tropical Pharmacology Lab is a world-leading academic research group within antibody technologies with a special focus on the discovery of antibodies that target toxins and virulence factors, as well as antibodies with special binding properties (e.g. broadly-neutralizing, conditional binding, anatomically-targeted, enhanced effector functions etc.). We utilize both in vitro and in vivo antibody discovery techniques and collaborate with a large number of national and international partners to bring our basic and applied science discoveries beyond the lab. Therefore, the Tropical Pharmacology Lab is also engaged in many innovation and entrepreneurship activities, including spinout of companies.

The research group is headed by Professor Andreas Hougaard Laustsen-Kiel and is based in the section for Protein Science & Biotherapeutics at the Department of Biotechnology and Biomedicine. Currently, the group employs about 30 full-time researchers and PhD students. We have an exceptionally collaborative spirit and host many talented students and guest researchers from abroad. We aim for scientific excellence through teamwork and ambition, which is supported by having an inclusive and dynamic environment with room for new ideas. See more:

Responsibilities and tasks
The project is funded by Innovation Fund Denmark and will be focused on developing nanobodies and nanobody constructs targeting virulence factors from pathogenic E. coli with the aim of developing sustainable solutions for reducing the impact of gastrointestinal infections. The role of the candidate will primarily be to perform experiments in the laboratory, as well as data analysis, and scientific publication.

The candidate should preferably have an entrepreneurial spirit and be interested in facilitating the transition of scientific discoveries into inventions and innovations that can be brought to life in society.

Applicants should hold a PhD in a life sciences discipline, have excellent communication skills, demonstrate scientific excellence, and be extensively trained in protein biochemistry, protein engineering, antibody discovery, and/or molecular/synthetic biology. In our research group, we highly value collaboration, and it will be expected that the candidates can demonstrate that he/she has a track record for successfully collaborating with his/her peers and students.

It is beneficial (but not mandatory) if the applicant has extensive experience with one or more of the following techniques:

  • Phage display technology
  • Antibody discovery
  • High-throughput methods for clone/antibody screening
  • Surface Plasmon Resonance, Isothermal Titration Calorimetry, Octet, or similar biophysics techniques
  • High-density peptide microarray design and analysis
  • Antigen isolation and purification
  • Recombinant protein expression and purification

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. 

More specifically in the Tropical Pharmacology Lab, we are a group of high performing younger scientists that share the vision that science is supposed to benefit humankind, especially underprivileged societies and/or societal groups. This shared vision with a very international outreach has created an academic environment that is ambitious and innovative fueled by an exceptionally collegially supportive attitude to both people and their work. We welcome people with all types of backgrounds and strive for diversity. Our research group is highly active in numerous outreach activities and our international travel agendas are typically busy. Finally, group members typically have an entrepreneurial attitude, resulting in the establishment of a number of spin-out biotech companies by group members.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

International candidates may in some cases be eligible for the Researcher Tax scheme: Danish Tax Authority. Successful application to this scheme is, however, not promised by DTU.

You can read more about career paths at DTU here.

The positions will be located at the DTU Lyngby campus in a newly established research building hosting ultra-modern laboratories for antibody discovery and phage display technology with neighboring laboratories with state-of-the-art facilities for protein science and proteomics. 

Further Information
Additional information may be obtained from Professor Andreas Hougard Laustsen-Kiel,

Application procedure
Please submit your online application no later than 30 January 2022 (Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Academic Diplomas (MSc/PhD)
  • List of publications

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.