PhD scholarship in the Discovery and Engineering of Oxidoreductases for the Conversion of Recalcitrant Polysaccharides from Biomass

mandag 21 jun 21

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Frist 31. juli 2021
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A PhD position is available in the Protein Glycoscience and Biotechnology group, Protein Chemistry and Enzyme Technology section, Department of Biotechnology and Biomedicine. One research focus area of this group, headed by Prof. Maher Abou Hachem, is the discovery and biotechnological applications of oxidoreductases.

The PhD research project is a collaboration with the lab of Jean Guy Berrin (INRA, Aix-Marseille University Marseille, France), who are leading experts in fungal bioamss active enzymes. The project goal the discovery and engineering of carbohydrate active flavo-oxidoreductases for applications within biomass processing.

Responsibilities and qualifications

  • Based on sequence analyses, select new flavo-enzyme candidates for expression, enzymatic and electrochemical characterisation
  • Determine the crystal structures of relevant enzymes and combine with bioinformatics to decode their mode of action
  • Rational engineering of selected enzymes and evaluation of the engineered variants
  • Scientific, dissemination and collaboration activities related to the project
  • Take part in teaching and supervision within protein chemistry and enzymology

You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.

Desired candidate academic and personal profile:

  • An outstanding academic record with a strong background in chemistry, biochemistry, enzymology or related study fields is critical
  • Previous experience in oxidoreductase chemistry, electrochemistry, carbohydrate analytical techniques are good merits
  • A basic background in bioinformatics and/or structural biology is a good asset
  • Independent and self-driven 
  • Very ambitious and hard-working
  • Passionate about research and enjoys a relaxed informal work environment

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide

Assessment

The assessment of candidates will be made by Prof Maher Abou Hachem. 

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.  


Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. 

You can read more about career paths at DTU here

Further information

Further information may be obtained from Maher Abou Hachem, tel.: +45 4525 2732, e-mail: maha@bio.dtu.dk.

You can read more about the Department of Biotechnology and Biomedicine at www.bioengineering.dtu.dk and about the Protein Chemistry and Enzyme Technology section here.   

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark

Application procedure
Your complete online application must be submitted no later than 31 July 2021 (Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)
  • List of publications if any
  • References

You may apply prior to ob­tai­ning your master's degree but cannot begin before having received it.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

DTU Bioengineering (Department of Biotechnology and Biomedicine) is an important contributor to the areas of biotechnology, food technology and human health, through the advances we make in research, technology and innovation and through the training and education of first-class MScs and PhDs in bio-engineering.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.